SCHEMBL140640

SCHEMBL140640

Nc1nc(Cl)cc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL654863 0.85
SCHEMBL29364638 0.85
Hydrochloric Acid SCHEMBL28680674 0.83 HSP90AB1 (0.47)
Hydrochloric Acid SCHEMBL29742915 0.83 HSP90AB1 (0.47)
SCHEMBL29742952 0.83 HSP90AB1 (0.47)
SCHEMBL536615 0.81
SCHEMBL150686 0.81
SCHEMBL21778799 0.81
SCHEMBL13485364 0.81
SCHEMBL2874699 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2284 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005212-A Porous coordination polymer with interpenetrating framework, preparation method and application of porous coordination polymer in ethane/ethylene high-temperature separation 南京工业大学 2025-05-16 CN claimed
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN claimed
CN-115650225-B Amino functionalized graphene oxide and preparation method and application thereof 陕西科技大学 2024-05-03 CN claimed
CN-111559981-B Biphenyl-pyrimidine conjugate and preparation method and application thereof 杭州庆正鸿科技有限公司 2023-08-01 CN claimed
CN-115650225-A Amino functionalized graphene oxide and preparation method and application thereof 陕西科技大学 2023-01-31 CN claimed
CN-115341388-A Preparation method of non-ironing antistatic anti-pilling polyester-cotton blended fabric 湖州纳尼亚实业有限公司 2022-11-15 CN claimed
CN-113549254-B Method for preparing modified vulcanized rubber and modified vulcanized rubber 中国科学技术大学 2022-10-28 CN claimed
CN-113999177-A Preparation method of 2-amino-4, 6-dichloropyrimidine 苏州艾缇克药物化学有限公司 2022-02-01 CN claimed
CN-109053590-B Method for preparing 4, 6-dichloro-2-aminopyrimidine 江苏富鼎化学有限公司 2021-10-29 CN claimed
CN-113549254-A Method for preparing modified vulcanized rubber and modified vulcanized rubber 中国科学技术大学 2021-10-26 CN claimed
WO-1993025539-A1 NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME Richter Gedeon Vegyészeti Gyár Rt. (HU) 1993-12-23 WO claimed
WO-1993025550-A1 NOVEL BIOLOGICALLY ACTIVE EBURNAMENINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME RICHETER GEDEON VEGYÉSZETI GYÁR RT. (HU) 1993-12-23 WO claimed
CN-1019575-B Production method of 2-amino-4, 6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1992-12-23 CN claimed
US-4929729-A REACTION WITH PHOSPHOROUS OXYCHLORIDE, HYDROLYSIS, CHLORINATION ISHIHARA SANGYO KAISHA LTD. (JP) 1990-05-29 US claimed
CN-1035504-A 2-amino-4, the production method of 6-dichloro pyrimidine ISHIHARA SANGYO KAISHA (JP) 1989-09-13 CN claimed
EP-0329170-A2 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-08-23 EP claimed
EP-0267675-A2 Modified conjugated diene polymer and process for production thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-05-18 EP claimed
EP-0062439-B1 GUANIDINOPYRIMIDINES SMITHKLINE BECKMAN CORPORATION (US) 1985-03-20 EP claimed
EP-0030141-B1 HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-20 EP claimed
US-3991190-A Treatment of viral infections ISTITUTO CHEMIOTERAPICO ITALIANO S.P.A. (IT) 1976-11-09 US claimed