Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 14/20 | 0.71 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.47 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065313 | 0.91 | LIMK2 (0.72) | LIMK2MALT1 | |
| SCHEMBL14065321 | 0.90 | LIMK2 (0.88) | LIMK2 | |
| SCHEMBL14065314 | 0.83 | LIMK2 (0.76) | LIMK2 | |
| SCHEMBL14065261 | 0.83 | LIMK2 (1.00) | LIMK2 | |
| SCHEMBL14065280 | 0.82 | LIMK2 (0.90) | LIMK2 | |
| SCHEMBL14065311 | 0.81 | LIMK2 (0.72) | LIMK2 | |
| SCHEMBL14065262 | 0.81 | LIMK2 (0.89) | LIMK2 | |
| SCHEMBL14065257 | 0.81 | LIMK2 (0.89) | LIMK2 | |
| SCHEMBL14065282 | 0.81 | LIMK2 (0.80) | LIMK2 | |
| SCHEMBL14065264 | 0.81 | LIMK2 (0.89) | LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423043-B2 | 4-Piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine compounds | LEXICON PHARMACEUTICALS, INC. (US) | 2008-09-09 | — | — | US | disclosed |