SCHEMBL14065902

SCHEMBL14065902

CC(=O)C1=NN(c2ccc(C(=O)O)cc2)C(=O)C1=CC=Cc1ccc(N(C)C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.60
KMT2A Q03164 10/20 0.60
MEN1 O00255 8/20 0.60
MAPK1 P28482 7/20 0.60
TDP1 Q9NUW8 4/20 0.60
L3MBTL1 Q9Y468 4/20 0.60
HTT P42858 3/20 0.60
LMNA P02545 2/20 0.60
PKM P14618 2/20 0.60
OPRK1 P41145 1/20 0.60
ALDH1A1 P00352 7/20 0.47
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MDM2 Q00987 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
KAT8 Q9H7Z6 1/20 0.45
POLB P06746 1/20 0.45
APP P05067 4/20 0.44
SNCA P37840 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14074481 0.88 KMT2A (0.48) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL9854320 0.88 KMT2A (0.78) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL13863860 0.85 MAPT (0.74) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL11936879 0.82 MAPT (0.70) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL13528778 0.82 MAPT (0.58) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL6655240 0.82 MAPT (0.58) MAPTKMT2AMEN1MAPK1TDP1
Ammonia Solution, Strong SCHEMBL6655370 0.81 MAPT (0.57) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL14196851 0.81 MEN1 (0.62) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL5706392 0.78 MAPT (0.73) MAPTKMT2AMEN1MAPK1TDP1
SCHEMBL12589907 0.78 MAPT (0.62) MAPTKMT2AMEN1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 US disclosed