Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17210748 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8331554 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8331016 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8331851 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL9428050 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8326349 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8327727 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8327722 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL524061 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 | |
| SCHEMBL8328567 | 0.90 | KMT2A (0.61) | KMT2AMAPK1GRM5CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262477-B1 | ANTI-ACID-FAST BACTERIAL AGENTS CONTAINING PYRIDONECARBOXYLIC ACIDS AS THE ACTIVE INGREDIENT | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |