Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522222 | 0.86 | POLB (0.64) | SORDPOLBKCNH2HTR1ADRD4 | |
| SCHEMBL13711971 | 0.85 | KCNH2 (0.71) | POLBKCNH2HTR1ADRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2517441 | 0.85 | POLB (0.62) | SORDPOLBKCNH2HTR1ADRD4 | |
| SCHEMBL29857922 | 0.84 | PLD1 (0.73) | SORDPOLBKCNH2PLD1KDM4E | |
| SCHEMBL21353591 | 0.84 | — | — | |
| SCHEMBL15800694 | 0.84 | PLD1 (0.73) | SORDPOLBKCNH2PLD1KDM4E | |
| SCHEMBL9492781 | 0.83 | KCNH2 (0.69) | POLBKCNH2HTR1ADRD4 | |
| SCHEMBL23252409 | 0.82 | POLB (0.59) | POLBKCNH2HTR1ATHRBNPSR1 | |
| SCHEMBL3867807 | 0.82 | KDM4E (0.64) | POLBKCNH2HTR1APLD1KDM4E | |
| SCHEMBL7297746 | 0.82 | POLB (0.59) | POLBKCNH2HTR1ATHRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |