Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 18/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626879 | 0.79 | APP (0.58) | APPTLR9TLR7 | |
| SCHEMBL13290926 | 0.78 | APP (0.72) | APP | |
| SCHEMBL912762 | 0.74 | APP (1.00) | APP | |
| SCHEMBL14076026 | 0.74 | APP (0.71) | APP | |
| SCHEMBL14067490 | 0.73 | APP (0.56) | APP | |
| SCHEMBL15095457 | 0.72 | APP (0.69) | APPTLR9 | |
| SCHEMBL17626739 | 0.72 | APP (0.51) | APPTLR9TLR7 | |
| SCHEMBL14076014 | 0.72 | APP (1.00) | APP | |
| SCHEMBL17626875 | 0.72 | APP (0.51) | APPTLR9TLR7 | |
| SCHEMBL16212916 | 0.71 | TLR9 (0.81) | APPTLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | APP, PSEN1, MAPT | APP 1/4885TLR9 4883/4885TLR7 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.