Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CCR4 | P51679 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025153 | 1.00 | NPSR1 (0.52) | NPSR1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL14045749 | 0.89 | NPSR1 (0.55) | NPSR1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL14045752 | 0.87 | NPSR1 (0.56) | NPSR1ALDH1A1USP2PKMRECQL | |
| SCHEMBL14025171 | 0.87 | NPSR1 (0.50) | NPSR1ALDH1A1USP2PKMRECQL | |
| SCHEMBL4924392 | 0.83 | NPSR1 (0.53) | NPSR1OPRM1OPRD1ALDH1A1USP2 | |
| SCHEMBL4924403 | 0.83 | NPSR1 (0.53) | NPSR1OPRM1OPRD1ALDH1A1USP2 | |
| SCHEMBL14067958 | 0.83 | NPSR1 (0.53) | NPSR1OPRM1OPRD1ALDH1A1USP2 | |
| SCHEMBL4922803 | 0.82 | NPSR1 (0.52) | NPSR1OPRM1OPRD1TSHRMEN1 | |
| SCHEMBL4922817 | 0.82 | NPSR1 (0.52) | NPSR1OPRM1OPRD1TSHRMEN1 | |
| SCHEMBL14025001 | 0.81 | NPSR1 (0.51) | NPSR1OPRM1OPRD1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |