Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 13/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930134 | 1.00 | KCNH2 (0.49) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL9964782 | 0.95 | KCNH2 (0.49) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL9968650 | 0.93 | KCNH2 (0.41) | KCNH2F10P2RX7 | |
| SCHEMBL9968573 | 0.90 | KCNH2 (0.45) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL13429742 | 0.89 | KCNH2 (0.37) | KCNH2MAOACYP2C19 | |
| SCHEMBL9930387 | 0.89 | KCNH2 (0.51) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL9964773 | 0.89 | KCNH2 (0.51) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL13429763 | 0.89 | KCNH2 (0.51) | KCNH2MAOBMAOACYP2C19F10 | |
| SCHEMBL9930295 | 0.86 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL9968586 | 0.85 | KCNH2 (0.47) | KCNH2MAOBMAOACYP2C19F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |