Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 19/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 17/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472277 | 0.84 | DPP4 (0.52) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL1407743 | 0.82 | DPP4 (0.70) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL4472292 | 0.82 | DPP4 (0.44) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL1408338 | 0.82 | DPP4 (0.49) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL1408142 | 0.81 | DPP4 (0.51) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL1408438 | 0.81 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL1408010 | 0.81 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL1408043 | 0.81 | DPP4 (0.50) | DPP4CYP1A2CYP3A4CYP2C19DPP8 | |
| SCHEMBL1408021 | 0.80 | DPP4 (0.62) | DPP4DPP8DPP9 | |
| SCHEMBL1407424 | 0.79 | DPP4 (0.57) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836206-B1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL MYERS SQUIBB CO (US) | 2011-03-09 | — | — | EP | disclosed |