Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | THRB | P10828 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14077696 | 0.85 | KDM4E (0.45) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077648 | 0.84 | MAPT (0.69) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077667 | 0.82 | MAPT (0.64) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9061457 | 0.80 | MAPT (0.67) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077649 | 0.79 | MAPT (0.54) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9867691 | 0.77 | MAPT (0.54) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077652 | 0.76 | MAPT (0.47) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077727 | 0.76 | KDM4E (0.54) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077658 | 0.75 | MAPT (0.52) | MAPTTHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14077673 | 0.75 | KDM4E (0.43) | MAPTTHRBSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425406-B2 | Lithographic printing plate precursor and lithographic printing method | FUJIFILM CORPORATION (JP) | 2008-09-16 | — | — | US | disclosed |