SCHEMBL14077752

SCHEMBL14077752

CCCCCCN1c2ccccc2C(C)(C)C12C=Cc1c(ccc3ccccc13)O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
KDM4E B2RXH2 8/20 0.46
SMN1; SMN2 Q16637 7/20 0.46
THRB P10828 5/20 0.46
PKM P14618 2/20 0.46
ALOX12 P18054 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 7/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
LMNA P02545 5/20 0.46
RECQL P46063 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
PLIN1 O60240 1/20 0.46
TSHR P16473 1/20 0.46
PLIN5 Q00G26 1/20 0.46
ABHD5 Q8WTS1 1/20 0.46
HTT P42858 5/20 0.45
NPSR1 Q6W5P4 4/20 0.40
ALPG P10696 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16315817 0.99 MAPT (0.47) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL8688287 0.96 MAPT (0.47) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL8862466 0.92 MAPT (0.49) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL8680024 0.87 SMN1; SMN2 (0.50) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL14552866 0.87 MAPT (0.60) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL16313217 0.86 MAPT (0.44) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL13895709 0.85 SMN1; SMN2 (0.48) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL14647599 0.84 SMN1; SMN2 (0.48) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL14077756 0.82 SMN1; SMN2 (0.50) MAPTKDM4ESMN1; SMN2THRBPKM
SCHEMBL29931020 0.82 MAPT (0.63) MAPTKDM4ESMN1; SMN2THRBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed