Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078571 | 1.00 | ACKR3 (0.47) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13391005 | 0.91 | ACKR3 (0.47) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL14077861 | 0.89 | ACKR3 (0.45) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13390965 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13391222 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13409694 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13391261 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13391111 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13409692 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 | |
| SCHEMBL13391202 | 0.85 | ACKR3 (0.42) | ACKR3TBK1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008108957-A2 | PIPERIDINYL-PIPERIDINE AND PIPERAZINYL-PIPERIDINE FOR USE IN THE TREATMENT OF DIABETES OR PAIN | SCHERING CORPORATION (US) | 2008-09-12 | — | — | WO | disclosed |