Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ESRRG | P62508 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | HTR6 | P50406 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | GBA1 | P04062 | 1/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857990 | 0.95 | ESR1 (0.70) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857632 | 0.92 | ESR1 (0.66) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857878 | 0.91 | ESR1 (0.80) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857671 | 0.91 | ESR1 (0.80) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857672 | 0.90 | ESR1 (0.63) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857191 | 0.90 | ESR1 (0.63) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857951 | 0.90 | ESR1 (0.78) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL9857681 | 0.90 | ESR1 (0.63) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL8915491 | 0.88 | ESR1 (0.61) | ESR1ESR2MAPTESRRGMEN1 | |
| SCHEMBL2087896 | 0.88 | ESR1 (0.61) | ESR1ESR2MAPTESRRGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227814-A1 | Selective Estrogen Receptor Modulators | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227814-A1 | Selective Estrogen Receptor Modulators | GPER1, ESR2, ESR1 | ESR1 3/4885ESR2 2/4885MAPT 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.