Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 19/20 | 1.00 |
| ▸ | DRD2 | P14416 | 14/20 | 1.00 |
| ▸ | DRD4 | P21917 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243567 | 1.00 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL13079532 | 1.00 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL1407749 | 1.00 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL3980374 | 1.00 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL1407940 | 1.00 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| Hydrochloric Acid SCHEMBL1407735 | 0.99 | DRD3 (0.98) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| Hydrochloric Acid SCHEMBL4259820 | 0.99 | DRD3 (0.98) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL11914910 | 0.94 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL12313275 | 0.94 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 | |
| SCHEMBL378184 | 0.94 | DRD3 (1.00) | DRD3KCNH2DRD2DRD4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917013-B1 | USE OF AZABICYCLO HEXANE DERIVATIVES | GLAXO GROUP LTD (GB) | 2011-03-09 | — | — | EP | claimed |
| EP-1745040-B9 | AZABICYCLO(3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LTD (GB) | 2010-06-02 | — | — | EP | claimed |
| EP-1745040-B1 | AZABICYCLO(3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LTD (GB) | 2009-12-09 | — | — | EP | claimed |