Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 4/20 | 0.50 |
| ▸ | CYCS | P99999 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173908 | 1.00 | TOP1 (0.51) | TOP1STAT3STAT1TERTCYCS | |
| SCHEMBL14080609 | 1.00 | TOP1 (0.51) | TOP1STAT3STAT1TERTCYCS | |
| SCHEMBL25395411 | 1.00 | TOP1 (0.51) | TOP1STAT3STAT1TERTCYCS | |
| SCHEMBL432185 | 0.92 | KDM4E (0.46) | TOP1TERTHTTSMN1; SMN2 | |
| SCHEMBL29822398 | 0.92 | KDM4E (0.46) | TOP1TERTHTTSMN1; SMN2 | |
| SCHEMBL18795854 | 0.91 | TOP1 (0.52) | TOP1STAT3STAT1TERTCYCS | |
| SCHEMBL29560659 | 0.90 | KDM4E (0.45) | TOP1TERTHTTSMN1; SMN2 | |
| SCHEMBL9418754 | 0.90 | KDM4E (0.45) | TOP1TERTHTTSMN1; SMN2 | |
| SCHEMBL601668 | 0.90 | KDM4E (0.45) | TOP1TERTHTTSMN1; SMN2 | |
| SCHEMBL599851 | 0.90 | KDM4E (0.45) | TOP1TERTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324342-B1 | Porphyrin coordination polymer nanospheres and nanorods | SANDIA CORPORATION (US) | 2012-12-04 | — | — | US | claimed |
| US-8530614-B1 | Porphyrin coordination polymer nanospheres and nanorods | SANDIA CORPORATION (US) | 2013-09-10 | — | — | US | disclosed |
| US-8324342-B1 | Porphyrin coordination polymer nanospheres and nanorods | SANDIA CORPORATION (US) | 2012-12-04 | — | — | US | disclosed |