SCHEMBL14082147

SCHEMBL14082147

OC1(C(CN2CCCCC2)c2cccc(OC(F)(F)F)c2)CCCCC1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.84
SLC6A4 P31645 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173617 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL3955505 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL3960937 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4625301 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4626427 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL3955973 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL3959836 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4706062 0.91 SLC6A2 (0.76) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL3959906 0.91 SLC6A2 (1.00) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL3960306 0.91 SLC6A2 (1.00) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7419980-B2 Fused-aryl and heteroaryl derivatives and methods of their use WYETH (US) 2008-09-02 US disclosed
CN-1898222-A Substituted aryl cycloalkanol derivatives and methods of their use WYETH CORP (US) 2007-01-17 CN disclosed
CN-1897950-A Fused aryl and heteroaryl derivatives and methods of use thereof WYETH CORP (US) 2007-01-17 CN disclosed