Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.67 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407973 | 0.80 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL4482928 | 0.79 | DPP4 (0.71) | DPP4DPP8CNR1THRBTP53 | |
| SCHEMBL4482924 | 0.79 | DPP4 (0.82) | DPP4DPP8CNR1THRB | |
| SCHEMBL1408245 | 0.79 | DPP4 (0.75) | DPP4DPP8CNR1THRBALDH1A1 | |
| SCHEMBL1408141 | 0.76 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL1408041 | 0.74 | DPP4 (0.43) | DPP4DPP8 | |
| SCHEMBL1408436 | 0.74 | DPP4 (0.49) | DPP4DPP8 | |
| SCHEMBL1408336 | 0.74 | DPP4 (0.42) | DPP4DPP8 | |
| SCHEMBL1408009 | 0.74 | DPP4 (0.50) | DPP4DPP8 | |
| SCHEMBL1408020 | 0.72 | DPP4 (0.52) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836206-B1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL MYERS SQUIBB CO (US) | 2011-03-09 | — | — | EP | disclosed |