SCHEMBL1408562

SCHEMBL1408562

C=Cc1ccc(SCC2CO2)cc1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.31
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402675 0.84 DRD4 (0.36) ALDH1A1TSHRDRD4
SCHEMBL15700020 0.79 CHRM2 (0.40) ALDH1A1TSHRDRD4
SCHEMBL1402587 0.79 DRD4 (0.34) ALDH1A1TSHRDRD4
SCHEMBL83271 0.79 CHRM2 (0.40) ALDH1A1TSHRDRD4
SCHEMBL1402362 0.76 DRD4 (0.38) DRD4
SCHEMBL83272 0.76 DRD4 (0.33) DRD4
SCHEMBL8847058 0.76 DRD4 (0.48) ALDH1A1TSHRDRD4
SCHEMBL10533009 0.76 CRBN (0.45) ALDH1A1
SCHEMBL7282254 0.76 CRBN (0.45) ALDH1A1TSHRDRD4
SCHEMBL5513100 0.75 DRD4 (0.47) ALDH1A1TSHRDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560060-B1 Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production MGC FILSEET CO LTD (JP) 2011-03-09 EP disclosed
US-7350917-B2 Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens MGC FILSEET CO., LTD. (JP) 2008-04-01 US disclosed
US-20050168690-A1 Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens FUJI KASEI CO., LTD. (JP) 2005-08-04 US disclosed
EP-1560060-A1 Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production Fuji Kasei Co., Ltd. (JP) 2005-08-03 EP disclosed