Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | PI4KA | P42356 | 2/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.57 |
| ▸ | AHCY | P23526 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870064 | 0.96 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL13870051 | 0.90 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL4551803 | 0.84 | ADORA2A (0.91) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL27499558 | 0.83 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL23228230 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL28228476 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL28176129 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL21469779 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL1741560 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL9484927 | 0.82 | ADORA2A (0.88) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313751-B1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2008-09-17 | — | — | EP | disclosed |