Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090837 | 0.89 | BRD4 (0.49) | NPSR1MEN1KMT2AMAPTPOLB | |
| SCHEMBL14090848 | 0.83 | BRD4 (0.39) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14090868 | 0.82 | NPSR1 (0.36) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14090856 | 0.81 | C3AR1 (0.40) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14090986 | 0.80 | NPSR1 (0.44) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14090845 | 0.80 | BRD4 (0.53) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL4989716 | 0.79 | C3AR1 (0.51) | MAPTPOLBC3AR1BRD4BRD2 | |
| SCHEMBL14090857 | 0.79 | NPSR1 (0.36) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14090865 | 0.78 | CA1 (0.37) | KMT2AALDH1A1KDM4EC3AR1 | |
| SCHEMBL14090858 | 0.77 | NPSR1 (0.42) | NPSR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | NPSR1 474/4885MEN1 2114/4885KMT2A 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.