Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 6/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353358 | 1.00 | AR (0.52) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4037187 | 0.85 | MIF (0.67) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13802615 | 0.85 | AR (0.46) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13802618 | 0.85 | AR (0.46) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4156277 | 0.84 | AR (0.51) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8348785 | 0.84 | MIF (0.55) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4157315 | 0.84 | MIF (0.55) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4157311 | 0.84 | MIF (0.55) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13802681 | 0.82 | AR (0.51) | ARTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4156050 | 0.81 | MIF (0.55) | ARTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411072-B2 | Tricyclic steroid hormone nuclear receptor modulators | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-7411072-B2 | Tricyclic steroid hormone nuclear receptor modulators | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |