Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.70 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078167 | 0.88 | TSHR (0.71) | CSF1RMAPK8MAPK10POLBTSHR | |
| SCHEMBL14078168 | 0.88 | MAPK8 (0.74) | CSF1RMAPK8MAPK10 | |
| SCHEMBL13147776 | 0.82 | CSF1R (1.00) | CSF1RMAPK10 | |
| SCHEMBL13180540 | 0.75 | CSF1R (1.00) | CSF1R | |
| SCHEMBL16050404 | 0.75 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13148022 | 0.74 | CSF1R (0.69) | CSF1R | |
| SCHEMBL13148055 | 0.74 | CSF1R (0.69) | CSF1R | |
| SCHEMBL13148110 | 0.74 | CSF1R (0.78) | CSF1R | |
| SCHEMBL13148115 | 0.74 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13148096 | 0.73 | CSF1R (0.77) | CSF1RMAPK10POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427683-B2 | c-fms kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-23 | — | — | US | disclosed |