Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933352 | 0.86 | HDAC3 (0.41) | POLBTLR7MEN1KMT2AHDAC3 | |
| SCHEMBL13932953 | 0.79 | USP2 (0.45) | POLBTLR7MEN1KMT2AHDAC3 | |
| SCHEMBL14706004 | 0.76 | HDAC3 (0.34) | POLBTLR7MEN1KMT2AHDAC3 | |
| SCHEMBL13493223 | 0.75 | HRH3 (0.35) | SLC6A4MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL13493234 | 0.74 | TSHR (0.45) | POLBHTR5AHDAC3HDAC1HDAC2 | |
| SCHEMBL14706185 | 0.73 | HDAC6 (0.41) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL13493226 | 0.71 | HDAC1 (0.40) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL13521690 | 0.69 | HDAC3 (0.46) | POLBTLR7KMT2AACHEHDAC3 | |
| SCHEMBL13933350 | 0.68 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL13493193 | 0.68 | HRH4 (0.35) | SLC6A4MEN1KMT2AS1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103847-A2 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | ALLACCEM, INCORPORATED (US) | 2008-08-28 | — | — | WO | disclosed |