SCHEMBL14098681

SCHEMBL14098681

COC(=N)Cc1cc(Cl)ccc1OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PTGER1 P34995 16/20 0.54
▸ CCR5 P51681 1/20 0.49
▸ STAT3 P40763 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4720651 0.99 PTGER1 (0.53) PTGER1CCR5STAT3
SCHEMBL2111974 0.81 PTGER1 (0.59) PTGER1
SCHEMBL2110600 0.81 PTGER1 (0.62) PTGER1
SCHEMBL4721320 0.80 PTGER1 (0.60) PTGER1STAT3
SCHEMBL14098679 0.80 PTGER1 (0.49) PTGER1
SCHEMBL2954443 0.79 MAPT (0.60) PTGER1
SCHEMBL4722982 0.78 PTGER1 (0.53) PTGER1CCR5STAT3
Hydrochloric Acid SCHEMBL4721457 0.78 PTGER1 (0.48) PTGER1
SCHEMBL2114834 0.78 PTGER1 (0.53) PTGER1CCR5
SCHEMBL4720836 0.77 PTGER1 (0.56) PTGER1CCR5STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207708-A1 Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders GLAXO GROUP LIMITED (GB) 2008-08-28 — — US disclosed
US-20080207708-A1 Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders GLAXO GROUP LIMITED (GB) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207708-A1 Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders PTGER1, PTGER2, PTGER4 PTGER1 1/4885CCR5 1187/4885STAT3 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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