Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 4/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.53 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409952 | 1.00 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL28113266 | 1.00 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1117046 | 0.98 | CPA1 (0.56) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1410060 | 0.98 | CPA1 (0.56) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1410324 | 0.98 | CPA1 (0.56) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1410255 | 0.96 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1410053 | 0.96 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| Potassium Ion SCHEMBL1410071 | 0.96 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL1410050 | 0.96 | CPA1 (0.55) | CPA1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL15290363 | 0.83 | CPA1 (0.52) | CPA1CACNA2D1CACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546112-B2 | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester | SANDOZ AG (CH) | 2013-10-01 | — | — | US | disclosed |
| EP-2294207-B1 | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester | SANDOZ AG (CH) | 2012-09-26 | — | — | EP | disclosed |
| US-20110165636-A1 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | SANDOZ AG (CH) | 2011-07-07 | — | — | US | disclosed |
| EP-2294207-A2 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | Sandoz AG (CH) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009141362-A2 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | SANDOZ AG (CH) | 2009-11-26 | — | — | WO | disclosed |