Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054517 | 0.86 | ADRB3 (0.63) | ADRB3BLMKDM4ETDP1MAPT | |
| SCHEMBL7150607 | 0.85 | ADRB3 (0.58) | ADRB3BLMKDM4ETDP1MAPT | |
| SCHEMBL7150572 | 0.79 | ADRB3 (0.55) | ADRB3BLMKDM4ETDP1MAPT | |
| Norepinephrine SCHEMBL14940777 | 0.79 | BLM (0.79) | ADRB3BLMKDM4ETDP1MAPT | |
| SCHEMBL4816386 | 0.78 | ADRB3 (0.61) | ADRB3BLMKDM4ETDP1MAPT | |
| SCHEMBL7168421 | 0.78 | ADRB3 (0.61) | ADRB3BLMKDM4ETDP1MAPT | |
| L-Norepinephrine SCHEMBL22551317 | 0.77 | BLM (0.82) | ADRB3BLMKDM4ETDP1MAPT | |
| Norepinephrine SCHEMBL22551316 | 0.77 | BLM (0.82) | ADRB3BLMKDM4ETDP1MAPT | |
| SCHEMBL3984857 | 0.76 | ADRB3 (1.00) | ADRB3ADRB2 | |
| SCHEMBL7120011 | 0.76 | ADRB3 (1.00) | ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |