Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947696 | 0.86 | CXCR2 (0.50) | CXCR2CXCR1 | |
| SCHEMBL14100379 | 0.82 | CXCR2 (0.69) | CXCR2CXCR1 | |
| SCHEMBL14100815 | 0.82 | CXCR2 (0.58) | CXCR2CXCR1 | |
| SCHEMBL14621813 | 0.81 | CXCR2 (0.47) | CXCR2CXCR1 | |
| SCHEMBL13948182 | 0.80 | CXCR2 (0.48) | CXCR2CXCR1 | |
| SCHEMBL14100234 | 0.80 | CXCR2 (0.57) | CXCR2CXCR1 | |
| SCHEMBL14100486 | 0.80 | CXCR2 (0.67) | CXCR2CXCR1 | |
| SCHEMBL14100317 | 0.78 | CXCR1 (0.59) | CXCR2CXCR1 | |
| SCHEMBL14100466 | 0.78 | CXCR2 (0.58) | CXCR2CXCR1 | |
| SCHEMBL13208159 | 0.78 | CXCR1 (1.00) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |