Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 19/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 19/20 | 0.55 |
| ▸ | CCR7 | P32248 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 2/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13207787 | 1.00 | CXCR1 (0.55) | CXCR1CXCR2CCR7CXCR3CCR6 | |
| SCHEMBL13208716 | 0.90 | CXCR1 (0.69) | CXCR1CXCR2CCR7CXCR3CCR6 | |
| SCHEMBL13227359 | 0.90 | CXCR1 (0.69) | CXCR1CXCR2CCR7CXCR3CCR6 | |
| SCHEMBL13207779 | 0.89 | CXCR2 (0.52) | CXCR1CXCR2CCR7CXCR3CCR6 | |
| SCHEMBL13227417 | 0.89 | CXCR1 (0.44) | CXCR1CXCR2CCR7CXCR3CCR6 | |
| SCHEMBL13227414 | 0.88 | CXCR2 (0.46) | CXCR1CXCR2CCR6 | |
| SCHEMBL13207777 | 0.88 | CXCR2 (0.46) | CXCR1CXCR2CCR6 | |
| SCHEMBL13207786 | 0.86 | CXCR2 (0.41) | CXCR1CXCR2CXCR3CCR6CCR4 | |
| SCHEMBL14100447 | 0.86 | CXCR2 (0.41) | CXCR1CXCR2CXCR3CCR6CCR4 | |
| SCHEMBL14100618 | 0.86 | CXCR2 (0.68) | CXCR1CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |