Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 19/20 | 0.67 |
| ▸ | CXCR2 | P25025 | 19/20 | 0.67 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208180 | 0.86 | CXCR1 (0.84) | CXCR1CXCR2CCR6 | |
| SCHEMBL13208171 | 0.81 | CXCR2 (0.82) | CXCR1CXCR2 | |
| SCHEMBL13208153 | 0.80 | CXCR1 (1.00) | CXCR1CXCR2CCR6 | |
| SCHEMBL13208155 | 0.79 | CXCR1 (0.71) | CXCR1CXCR2 | |
| SCHEMBL13208144 | 0.79 | CXCR1 (1.00) | CXCR1CXCR2 | |
| SCHEMBL13208169 | 0.79 | CXCR1 (1.00) | CXCR1CXCR2 | |
| SCHEMBL13208141 | 0.78 | CXCR1 (1.00) | CXCR1CXCR2 | |
| SCHEMBL13208140 | 0.78 | CXCR1 (1.00) | CXCR1CXCR2 | |
| SCHEMBL13208132 | 0.78 | CXCR1 (1.00) | CXCR1CXCR2 | |
| SCHEMBL13208166 | 0.78 | CXCR1 (1.00) | CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |