Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.69 |
| ▸ | CXCR1 | P25024 | 17/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100360 | 0.88 | CXCR2 (0.79) | CXCR2CXCR1 | |
| SCHEMBL13227287 | 0.88 | CXCR2 (0.79) | CXCR2CXCR1 | |
| SCHEMBL13208160 | 0.88 | CXCR2 (0.79) | CXCR2CXCR1 | |
| SCHEMBL13208185 | 0.87 | CXCR1 (0.80) | CXCR2CXCR1 | |
| SCHEMBL13208192 | 0.83 | CXCR1 (0.71) | CXCR2CXCR1 | |
| SCHEMBL14511867 | 0.82 | CXCR2 (0.75) | CXCR2CXCR1 | |
| SCHEMBL13208127 | 0.82 | CXCR1 (1.00) | CXCR2CXCR1 | |
| SCHEMBL13208258 | 0.81 | CXCR1 (0.78) | CXCR2CXCR1 | |
| SCHEMBL13208159 | 0.81 | CXCR1 (1.00) | CXCR2CXCR1 | |
| SCHEMBL13208141 | 0.81 | CXCR1 (1.00) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |