SCHEMBL14101376

SCHEMBL14101376

Cc1cccc2sc(N3CCOCC3)nc12

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 9/20 0.70
RAB9A P51151 8/20 0.60
NPC1 O15118 5/20 0.60
MAPT P10636 7/20 0.60
L3MBTL1 Q9Y468 2/20 0.51
AR P10275 2/20 0.51
ALOX15 P16050 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9347476 0.82 SMN1; SMN2 (0.70) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL8514102 0.82 MAPT (0.60) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL22402844 0.82 SMN1; SMN2 (0.65) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL22402892 0.82 SMN1; SMN2 (0.65) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL25942725 0.80 SMN1; SMN2 (0.62) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL28716092 0.79 SMN1; SMN2 (0.65) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL14140633 0.79 SMN1; SMN2 (0.65) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL22263272 0.78 SMN1; SMN2 (0.64) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL15065374 0.78 MAPT (0.55) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1
SCHEMBL30718295 0.77 SMN1; SMN2 (0.62) SMN1; SMN2RAB9ANPC1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed