Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101638 | 1.00 | PIK3CA (0.41) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101628 | 0.98 | LIMK1 (0.40) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101627 | 0.98 | LIMK1 (0.40) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101571 | 0.97 | LIMK1 (0.38) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101639 | 0.95 | CYP1A2 (0.40) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101590 | 0.95 | CYP1A2 (0.40) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101645 | 0.95 | LIMK1 (0.38) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101574 | 0.95 | LIMK1 (0.38) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101572 | 0.95 | F9 (0.38) | PIK3CAPI4KAPI4KBLIMK1F9 | |
| SCHEMBL14101607 | 0.94 | CYP1A2 (0.39) | PIK3CAPI4KAPI4KBLIMK1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | CYBA, BPNT1, TYR | PIK3CA 4815/4885PI4KA 4381/4885PI4KB 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.