Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | F9 | P00740 | 3/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101457 | 1.00 | PIM3 (0.41) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101467 | 0.98 | PIM3 (0.42) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101430 | 0.98 | F9 (0.39) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101668 | 0.98 | F9 (0.39) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101536 | 0.98 | PIM3 (0.42) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101566 | 0.98 | PIM3 (0.42) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101433 | 0.97 | F9 (0.40) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101546 | 0.97 | F9 (0.40) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101429 | 0.97 | F9 (0.40) | PIM3F9LIMK1ROCK1PIK3CA | |
| SCHEMBL14101445 | 0.96 | F9 (0.39) | PIM3F9LIMK1ROCK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166594-A1 | BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME | CYBA, BPNT1, TYR | PIM3 2288/4885F9 3290/4885LIMK1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.