Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722916 | 0.86 | MAPT (0.61) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14101752 | 0.82 | SMN1; SMN2 (0.42) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4723923 | 0.81 | MAPT (0.56) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4719260 | 0.78 | MAPT (0.65) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4724375 | 0.77 | MAPT (0.58) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14102068 | 0.77 | SMN1; SMN2 (0.45) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4722956 | 0.76 | MAPT (0.63) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4720785 | 0.76 | MAPT (0.60) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4723759 | 0.75 | MAPT (0.59) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4722417 | 0.75 | MAPT (0.61) | GAASMN1; SMN2MAPTHTTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |