Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101931 | 0.87 | SMN1; SMN2 (0.54) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4722766 | 0.86 | MAPT (0.57) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14102010 | 0.83 | SMN1; SMN2 (0.46) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14102060 | 0.82 | SMN1; SMN2 (0.56) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4766556 | 0.78 | MAPT (0.60) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4720906 | 0.78 | MAPT (0.55) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14101756 | 0.77 | GAA (0.51) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14101809 | 0.77 | GAA (0.56) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL14102068 | 0.76 | SMN1; SMN2 (0.45) | GAASMN1; SMN2MAPTHTTHTR6 | |
| SCHEMBL4722092 | 0.75 | MAPT (0.66) | GAASMN1; SMN2MAPTHTTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |