Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.35 |
| ▸ | FLT3 | P36888 | 7/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4723873 | 0.99 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DCHEK1 | |
| Hydrochloric Acid SCHEMBL4724064 | 0.97 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DCHEK1 | |
| SCHEMBL14101915 | 0.95 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| Hydrochloric Acid SCHEMBL4723531 | 0.94 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| SCHEMBL4719833 | 0.92 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| SCHEMBL14101739 | 0.92 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| SCHEMBL4765721 | 0.91 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| SCHEMBL4722084 | 0.91 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| Hydrochloric Acid SCHEMBL4720194 | 0.91 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DHRH3 | |
| SCHEMBL4721102 | 0.91 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |