Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 11/20 | 0.43 |
| ▸ | FNTB | P49356 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102082 | 0.97 | MEN1 (0.46) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14101996 | 0.96 | MEN1 (0.45) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102078 | 0.86 | MEN1 (0.46) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102194 | 0.85 | MEN1 (0.44) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102073 | 0.85 | MEN1 (0.44) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14101997 | 0.85 | MEN1 (0.50) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102087 | 0.85 | MEN1 (0.49) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102196 | 0.85 | MEN1 (0.53) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102242 | 0.85 | MEN1 (0.49) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102245 | 0.83 | MEN1 (0.46) | MEN1KMT2AATMFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318993-B1 | SUBSTITUTED IMIDAZOLES AS DUAL HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS | SCHERING CORP (US) | 2008-08-20 | — | — | EP | disclosed |