Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14105659 | 1.00 | BACE1 (0.34) | BACE1BACE2CTSD | |
| SCHEMBL14105005 | 0.87 | BACE1 (0.34) | BACE1BACE2CTSD | |
| SCHEMBL7580253 | 0.86 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL13054864 | 0.86 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL13558854 | 0.83 | BACE1 (0.33) | BACE1BACE2CTSD | |
| SCHEMBL14106211 | 0.83 | BACE1 (0.36) | BACE1BACE2CTSD | |
| SCHEMBL14105014 | 0.83 | BACE1 (0.33) | BACE1BACE2CTSD | |
| SCHEMBL14105115 | 0.83 | SMN1; SMN2 (0.36) | BACE1 | |
| SCHEMBL7565071 | 0.79 | BACE1 (0.42) | BACE1BACE2CTSD | |
| SCHEMBL13054254 | 0.79 | BACE1 (0.42) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103351-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |