Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410669 | 1.00 | AKR1C3 (0.53) | AKR1C3TBXAS1MAPTALDH1A1KDM4E | |
| SCHEMBL17188865 | 0.84 | HDAC1 (0.41) | TBXAS1MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL10992573 | 0.83 | AKR1C3 (0.47) | AKR1C3TBXAS1MAPTALDH1A1KMT2A | |
| SCHEMBL10992577 | 0.83 | AKR1C3 (0.47) | AKR1C3TBXAS1MAPTALDH1A1KMT2A | |
| SCHEMBL17368452 | 0.82 | AKR1C3 (0.53) | AKR1C3TBXAS1ALDH1A1KDM4EAPEX1 | |
| SCHEMBL17273936 | 0.82 | AKR1C3 (0.53) | AKR1C3TBXAS1APEX1 | |
| SCHEMBL2272168 | 0.81 | AKR1C3 (0.52) | AKR1C3TBXAS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15758231 | 0.81 | AKR1C3 (0.52) | AKR1C3TBXAS1ALDH1A1MEN1KMT2A | |
| SCHEMBL2272174 | 0.81 | AKR1C3 (0.52) | AKR1C3TBXAS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15758230 | 0.81 | AKR1C3 (0.52) | AKR1C3TBXAS1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295410-A1 | HDAC inhibitor | Chroma Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |