Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107067 | 0.90 | MEN1 (0.45) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107078 | 0.89 | KDM4E (0.48) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107070 | 0.87 | MEN1 (0.43) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14103065 | 0.86 | MEN1 (0.45) | MEN1KMT2AKDM4EHSD17B10NOTCH1 | |
| SCHEMBL14106957 | 0.85 | MEN1 (0.47) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107205 | 0.84 | MEN1 (0.44) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL4744098 | 0.84 | MEN1 (0.48) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107085 | 0.84 | MEN1 (0.48) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107088 | 0.84 | MEN1 (0.48) | MEN1KMT2AKDM4EHSD17B10USP2 | |
| SCHEMBL14107087 | 0.83 | MEN1 (0.48) | MEN1KMT2AKDM4EHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |