Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107086 | 1.00 | MEN1 (0.49) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL13704068 | 0.89 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL13704070 | 0.89 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL4294419 | 0.89 | MEN1 (0.62) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL14582940 | 0.84 | MEN1 (0.53) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL14103352 | 0.82 | MEN1 (0.49) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL14103362 | 0.82 | MEN1 (0.49) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL14103364 | 0.82 | MEN1 (0.49) | MEN1KMT2AKDM4ENPC1PTGES | |
| SCHEMBL13704066 | 0.80 | MEN1 (0.72) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL4289448 | 0.80 | MEN1 (0.67) | MEN1KMT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |