Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107080 | 0.93 | KDM4E (0.49) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14106976 | 0.90 | KDM4E (0.49) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL4744098 | 0.89 | MEN1 (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14107088 | 0.89 | MEN1 (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14107085 | 0.89 | MEN1 (0.48) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL13704088 | 0.88 | KDM4E (0.53) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14107096 | 0.87 | KDM4E (0.46) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14103321 | 0.82 | MEN1 (0.43) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14106957 | 0.82 | MEN1 (0.47) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL14107074 | 0.81 | KMT2A (0.42) | KDM4EHSD17B10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |