Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.33 |
| ▸ | PPM1D | O15297 | 2/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25095403 | 1.00 | CDC25A (0.42) | CDC25ACDC25BLMNAGPBAR1CYP17A1 | |
| SCHEMBL4170618 | 1.00 | CDC25A (0.42) | CDC25ACDC25BLMNAGPBAR1CYP17A1 | |
| SCHEMBL4170622 | 1.00 | CDC25A (0.42) | CDC25ACDC25BLMNAGPBAR1CYP17A1 | |
| SCHEMBL13852405 | 1.00 | CDC25A (0.42) | CDC25ACDC25BLMNAGPBAR1CYP17A1 | |
| SCHEMBL8677904 | 1.00 | CDC25A (0.42) | CDC25ACDC25BLMNAGPBAR1CYP17A1 | |
| SCHEMBL8213600 | 0.86 | CDC25A (0.47) | CDC25ACDC25BLMNAGPBAR1PPM1D | |
| SCHEMBL3182269 | 0.86 | CDC25A (0.47) | CDC25ACDC25BLMNAGPBAR1PPM1D | |
| SCHEMBL13343106 | 0.86 | CDC25A (0.47) | CDC25ACDC25BLMNAGPBAR1PPM1D | |
| SCHEMBL3182273 | 0.86 | CDC25A (0.47) | CDC25ACDC25BLMNAGPBAR1PPM1D | |
| SCHEMBL13343110 | 0.86 | CDC25A (0.47) | CDC25ACDC25BLMNAGPBAR1PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |