Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.76 |
| ▸ | HTR2A | P28223 | 19/20 | 0.76 |
| ▸ | HTR2B | P41595 | 18/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119018 | 1.00 | HTR2C (0.76) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL13118965 | 1.00 | HTR2C (0.76) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL14110342 | 1.00 | HTR2C (0.76) | HTR2CHTR2AHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3556447 | 0.99 | HTR2C (0.74) | HTR2CHTR2AHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3556445 | 0.99 | HTR2C (0.74) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL14110497 | 0.86 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL13118872 | 0.86 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL14110383 | 0.86 | HTR2C (0.74) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL13118971 | 0.86 | HTR2C (0.74) | HTR2CHTR2AHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3555086 | 0.85 | HTR2C (0.98) | HTR2CHTR2AHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675859-B1 | MODULATORS OF SEROTONIN RECEPTORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-05 | — | — | EP | claimed |