Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.82 |
| ▸ | HTR2C | P28335 | 20/20 | 0.82 |
| ▸ | HTR2B | P41595 | 19/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119056 | 1.00 | HTR2A (0.82) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL13119055 | 1.00 | HTR2A (0.82) | HTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3561905 | 0.99 | HTR2A (0.80) | HTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3556011 | 0.99 | HTR2A (0.80) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL13119054 | 0.90 | HTR2A (1.00) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL13119053 | 0.90 | HTR2A (1.00) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL14110462 | 0.90 | HTR2A (1.00) | HTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3555493 | 0.89 | HTR2A (0.98) | HTR2AHTR2CHTR2BCYP3A4 | |
| Hydrochloric Acid SCHEMBL3554206 | 0.89 | HTR2A (0.98) | HTR2AHTR2CHTR2BCYP3A4 | |
| SCHEMBL13119057 | 0.84 | HTR2C (0.68) | HTR2AHTR2CHTR2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675859-B1 | MODULATORS OF SEROTONIN RECEPTORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-05 | — | — | EP | claimed |