Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 15/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14111445 | 0.92 | ADORA2A (0.46) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111561 | 0.90 | ADORA2A (0.46) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14453194 | 0.89 | ADORA2A (0.59) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111494 | 0.89 | ADORA2A (0.47) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111443 | 0.88 | ADORA2A (0.48) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111743 | 0.88 | ADORA2A (0.48) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111745 | 0.88 | ADORA2A (0.48) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111433 | 0.88 | ADORA2A (0.48) | ADORA2AADKDOT1LNPC1GALR3 | |
| SCHEMBL14111456 | 0.88 | HIF1A (0.44) | ADORA2AADKPAX8 | |
| SCHEMBL14111571 | 0.87 | ADORA2A (0.45) | ADORA2AADKDOT1LNPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |