Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 9/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12421709 | 0.81 | CSF1R (0.46) | CSF1RKIT | |
| SCHEMBL12667951 | 0.78 | CSF1R (0.43) | CSF1RKIT | |
| SCHEMBL12408163 | 0.76 | CSF1R (0.39) | CSF1RKIT | |
| SCHEMBL14401735 | 0.74 | CSF1R (0.68) | CSF1RKIT | |
| SCHEMBL13179761 | 0.73 | CSF1R (0.66) | CSF1RKIT | |
| SCHEMBL14117106 | 0.71 | CSF1R (0.54) | CSF1R | |
| SCHEMBL14405107 | 0.71 | CSF1R (0.59) | CSF1RKIT | |
| SCHEMBL14404991 | 0.71 | CSF1R (0.49) | CSF1RKIT | |
| SCHEMBL14405061 | 0.71 | CSF1R (0.48) | CSF1RKIT | |
| SCHEMBL14405023 | 0.69 | CSF1R (0.58) | CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414050-B2 | e.g. 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-19 | — | — | US | disclosed |