Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14124471 | 0.91 | IDO1 (0.41) | IDO1SLC22A12PDE2ABACE1KMT2A | |
| SCHEMBL14124487 | 0.91 | IDO1 (0.41) | IDO1SLC22A12PDE2ABACE1KMT2A | |
| SCHEMBL14124498 | 0.84 | PDE10A (0.39) | IDO1SLC22A12PDE2AKMT2AMAOA | |
| SCHEMBL14124490 | 0.80 | BACE1 (0.39) | IDO1SLC22A12PDE2ABACE1KMT2A | |
| SCHEMBL10041272 | 0.75 | BACE1 (0.43) | IDO1SLC22A12PDE2ABACE1KMT2A | |
| SCHEMBL15746018 | 0.74 | BACE1 (0.42) | SLC22A12CYP1A2PDE2ABACE1KMT2A | |
| SCHEMBL14124501 | 0.73 | TSHR (0.39) | IDO1SLC22A12CYP1A2KMT2AAKT1 | |
| SCHEMBL14124486 | 0.72 | TSHR (0.45) | SLC22A12CNR2 | |
| SCHEMBL14124469 | 0.72 | TSHR (0.45) | SLC22A12CNR2 | |
| SCHEMBL17952778 | 0.70 | IDO1 (0.43) | IDO1CYP17A1CYP1A2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120298979-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | UDC IRELAND LIMITED (IE) | 2012-11-29 | — | — | US | disclosed |