SCHEMBL1412474

SCHEMBL1412474

CCCCCCCCCC(C=C(C)C(N)=O)CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
GPR84 Q9NQS5 7/20 0.41
FFAR1 O14842 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.41
MAPT P10636 1/20 0.40
FAAH O00519 4/20 0.40
LAP3 P28838 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
SOAT1 P35610 1/20 0.39
KMT2A Q03164 1/20 0.39
CA2 P00918 1/20 0.39
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18094283 0.91 TSHR (0.42) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL3864827 0.84 FFAR1 (0.44) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL11024665 0.83 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL26624434 0.83 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL11659422 0.83 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL27513963 0.83 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL11661583 0.83 LCK (0.50) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL27493668 0.81 LCK (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL28742173 0.81 LCK (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL6577529 0.81 LCK (0.48) LCKPPARDZDHHC20ZDHHC2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2293826-B1 METHODS FOR MAKING ANTIMICROBIAL RESINS BAXTER INT (US) 2015-07-29 EP disclosed
US-8454984-B2 Antimicrobial resin compositions BAXTER INTERNATIONAL INC. (US) 2013-06-04 US disclosed
US-20130004557-A1 Antimicrobial Resin Compositions BAXTER HEALTHCARE S.A. (CH) 2013-01-03 US disclosed
US-8277826-B2 Methods for making antimicrobial resins BAXTER INTERNATIONAL INC. (US) 2012-10-02 US disclosed
EP-2293826-A1 METHODS FOR MAKING ANTIMICROBIAL RESINS Baxter International Inc. (US) 2011-03-16 EP disclosed
WO-2010008667-A1 METHODS FOR MAKING ANTIMICROBIAL RESINS BAXTER INTERNATIONAL INC (US) 2010-01-21 WO disclosed
US-20090324666-A1 METHODS FOR MAKING ANTIMICROBIAL RESINS BAXTER INTERNATIONAL INC. (US) 2009-12-31 US disclosed