Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310258 | 0.80 | KDM4E (0.51) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126859 | 0.79 | DYRK1A (0.41) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| Bromide SCHEMBL14126727 | 0.78 | DYRK1A (0.40) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| Hydrochloric Acid SCHEMBL14126717 | 0.78 | DYRK1A (0.40) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126724 | 0.77 | KDM4E (0.39) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126852 | 0.77 | KDM4E (0.39) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126594 | 0.77 | DYRK1A (0.39) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126723 | 0.77 | KDM4E (0.39) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL14126998 | 0.77 | DYRK1A (0.41) | DYRK1AHPGDHSD17B10POLBGPR35 | |
| SCHEMBL20559286 | 0.77 | CNR2 (0.53) | DYRK1AHPGDHSD17B10POLBGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | claimed |
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | disclosed |